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Preliminary results of the NIAID-sponsored clinical trial of remdesivir published in the New England Journal of Medicine, laying out the detailed benefits and limitations. The clinical trial is still ongoing

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Matthew Herper

STAT

Related: @EricTopol, CNN, New England Journal of Medicine (NEJM)

US funds AstraZeneca $1B for Oxford's Covid-19 vaccine, with 1000 people phase 1 study ongoing & 2 phase 3 studies to start in June (1000 people UK) & July (30000 people US). The company to supply 30M & 300M doses to UK & US.

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Vicky McKeever

CNBC

Related: @Reuters, Science Translational Medicine

Moderna's mRNA vaccine showed promising results in phase 1 trial, generated robust immune reaction, and it's dose dependent. Phase 2 to start soon with 600 people joining, and phase 3 in July with thousands of people

The company said its preliminary test in 8 healthy volunteers was safe. It is on an accelerated timetable to begin a larger human trial soon

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Denise Grady

New York Times

Related: @ScottGottliebMD, TIME (US magazine)

Confronting pandemic crisis: what other countries can teach us? Experience of Taiwan, New Zealand, African nations, & Germany pointing to science-driven, public health expertise, experience-dependent, timely, firm /decisive decision-making & action

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Henry Bair

San Francisco Chronicle

Related: The New Yorker, National Geographic, Los Angeles Times, Foreign Policy, CNN, The Atlantic, BBC

NIH launches a 2000-patient clinical trial to test if hydroxychloroquine and azithromycin can prevent COVID-19 patients from hospitalization or death

Study enrolling adults with mild to moderate COVID-19 in the United States.

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Staff Writer

National Institutes of Health (NIH) - US

Related: @AndyBiotech, Fox News, ClinicalTrials.gov

Abbott's ID Now fast Covid-19 test, claimed to show results within 5 to 13 minutes, used daily by White House and many hospitals, was found to miss infection for up to 48% (false negative). FDA issues warning of inaccuracy of this test

A study found that the Abbott ID Now machine was less accurate when it processed short, dry swabs

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Katie Thomas

New York Times

Related: NPR - National Public Radio, PR Newswire

Rare 'Kawasaki-like' inflammation, a treatable but potentially deadly disease, linked to Covid-19 children, cases spiked sharply in US and Europe

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Staff Writer

BBC

Related: @FaceTheNation, @DrMattMcCarthy, New York Times, @EricTopol, VOX, Channel 4 News -London UK, The Lancet

China researchers found two human neutralizing antibodies that block SARS-CoV-2 Spike from binding & entering human cells, made it a possible target for prophylactic (vaccine) & therapeutic (treatment) purposes for COVID-19 patients

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Staff Writer

Genetic Engineering & Biotechnology News

Related: Advanced Science News, Science

FDA impose tighter rules for Covid-19 antibody blood tests after hundreds of unproven and potentially fraudulent tests flooded US market amid the pandemic

At least 160 antibody tests for Covid-19 entered the U.S. without prior FDA scrutiny

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Thomas Burton

Wall Street Journal

Related: US FDA, Wired

Google & Apple to ban location tracking in their contact tracing apps, which may impact the effectiveness of those vital systems to public health during disease outbreaks and pandemic

The technology giants have laid out new rules for those using their upcoming exposure notification system

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Staff Writer

MIT Technology Review

Related: Business Insider, Wired

Japan to approve remdesivir in days following FDA's emergency approval for treating Covid-19. Tokyo asks Washington for steady supply while EMA starts reviewing to accelerate approval in Europe

Treatment could be available as early as mid-May

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Staff Writer

Nikkei Asian Review

Related: The Japan Times, Boston Globe, Fierce Biotech, New York Times, US FDA

Gilead's remdesivir 'has a clear cut significant positive effect' in shortening time to recovery for Covid-19 patients in a large NIH global clinical trial. FDA to grant Emergency Use Authorization soon

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Berkeley Lovelace Jr.

CNBC

Related: Science, @CarlosdelRio7, @adamfeuerstein, @eugenegu, @EricTopol, @ScottGottliebMD, YouTube, National Institutes of Health (NIH) - US, STAT

"The Manhattan Project" of Covid-19 era - a group of prominent scientists and billionaires working behind the scenes sharing findings with the White House, pushing for solutions to end the pandemic

They are working to cull the world’s most promising research on the pandemic, passing on their findings to policy makers and the White House

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Rob Copeland

Wall Street Journal

Related: The Kaiser Family Foundation, Daily Mail, MSNBC

Japan soon to approve remdesivir, Gilead's COVID-19 drug, in May, according to Prime Minister Shinzo Abe. If so, Japan will be the first country to approve this drug for treating COVID-19 patients

Antiviral drug will receive fast-track status if certified by another nation

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Staff Writer

Nikkei Asian Review

Related: @ScottGottliebMD, Kyodo News

“We’re ignoring everything we learned over the past century.” "Seattle’s Leaders Let Scientists Take the Lead. New York’s Did Not"...report on why New York and Seattle fared so different during Covid-19 pandemic

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Charles Duhigg

The New Yorker

Related: New York Times

As countries and states re-open economy, race of Covid-19 vaccine is on. France, Germany, and WHO to launch a $8B push on vaccine while US opt out. Merck to jump in by collaborating with Seattle-based Institute for Systems Biology

Other countries might not be quick to share. Time to speed up trials and ramp up manufacturing scale

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Scott Gottlieb

Wall Street Journal

Related: Merck, MarketWatch, Fierce Biotech, France 24

Novartis to run a 440 patients clinical trial of hydroxychloroquine against COVID-19, might help to settle the major debate of the efficacy and safety of the malaria drug that has been championed by Trump to treat COVID-19 patients

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Staff Writer

CNBC

Related: Endpoints News

More early data shows majority Covid-19 patients responding well to Gilead's drug remdesivir. Ex-FDA Commissioner suggested data may sufficient for Emergency Use Authorization

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Craig Jones

Benzinga

Related: @EricTopol, @Dereklowe, @maggieNYT, @eugenegu, @DrDenaGrayson, @DrEricDing, National Institutes of Health (NIH) - US, @ScottGottliebMD, YouTube, @SquawkCNBC, @jimcramer, STAT

AstraZeneca's phase 3 lung cancer trial of its flagship oncology drug Tagrisso stopped 2 years ahead of schedule due to 'overwhelming' benefit

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Natalie Grover

Endpoints News

Related: FiercePharma

Review of pharmacologic treatments that are being developed for Covid-19, including virology, targets, clinical trials, current clinical guidelines, treatment corresponding to disease stages

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James B. Cutrell

JAMA-Journal of American Medical Association

Related: BioCentury

Latest News

Remdesivir alone is not enough, researchers conclude in first major Covid-19 trial of the drug

22 May 2020, 9:01 PM, Maggie Fox, CNN


Remdesivir for the Treatment of Covid-19 — Preliminary Report

22 May 2020, 8:56 PM, John Beigel, New England Journal of Medicine (NEJM)


Covid-19 study details benefits of treatment with remdesivir, and also its limitations

22 May 2020, 8:54 PM, Matthew Herper, STAT


AstraZeneca receives $1 billion in US funding for Oxford University coronavirus vaccine

21 May 2020, 1:34 PM, Vicky McKeever, CNBC


Moderna's COVID-19 Vaccine Shows Promise, Generating Positive Immune Responses in an Early Study

18 May 2020, 4:33 PM, Alice Park, TIME (US magazine)


Coronavirus Vaccine Trial by Moderna Shows Promising Early Results

18 May 2020, 4:30 PM, Denise Grady, New York Times


Criticism of the Oxford Coronavirus Vaccine

18 May 2020, 2:05 PM, Derek Lowe, Science Translational Medicine


What African Nations Are Teaching the West About Fighting the Coronavirus

15 May 2020, 10:52 PM, Jina Moore, The New Yorker


NIH begins clinical trial of hydroxychloroquine and azithromycin to treat COVID-19

15 May 2020, 1:01 PM, Christopher Carbone, Fox News


FDA Cautions About Accuracy Of Widely Used Abbott Coronavirus Test

15 May 2020, 3:29 AM, Joe Neel, NPR - National Public Radio


Coronavirus: Children affected by rare Kawasaki-like disease

14 May 2020, 3:59 PM, Staff Writer, BBC


Twin antibodies show neutralizing activity against SARS-CoV-2

14 May 2020, 2:56 PM, VICTORIA CORLESS, Advanced Science News


NIH begins clinical trial of hydroxychloroquine and azithromycin to treat COVID-19

14 May 2020, 12:56 PM, Staff Writer, National Institutes of Health (NIH) - US


Coronavirus (COVID-19) Update: FDA Informs Public About Possible Accuracy Concerns with Abbott ID NOW Point-of-Care Test

14 May 2020, 3:34 AM, US FDA, PR Newswire


New Inflammatory Condition in Children Probably Linked to Coronavirus, Study Finds

13 May 2020, 4:39 PM, Pam Belluck, New York Times


What we know about the new Covid-19-linked illness in children

13 May 2020, 4:25 PM, Katherine Harmon Courage, VOX


Dr Liz Whittaker on rare inflammatory syndrome linked to Covid-19

13 May 2020, 4:15 PM, Matt Frei, Channel 4 News -London UK


Kawasaki-like disease: emerging complication during the COVID-19 pandemic

13 May 2020, 4:02 PM, Elizabeth Whittaker, The Lancet


A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2

13 May 2020, 2:53 PM, Shihua Li, Science


SARS-CoV-2 Spike Foiled by Antibody Duo

13 May 2020, 2:51 PM, Staff Writer, Genetic Engineering & Biotechnology News