Top News

Wuhan lockdown quarantine, once harshly criticized and bearing major unintended consequences, now believed by experts to have bought China and the world precious time to prepare for Covid-19 epidemic

PermaLink

Sharon Begley

STAT

Related: Dalla Lana School of Public Health, @WHO, @ecapobianco, @SCBriand, @GHS, @alexandraphelan, @T_Inglesby, Nature

"A crisper CRISPR" researchers at Broad Institute debut a super-precise version of the CRISPR tool that will offer greater control on what to edit, significantly reduce off-target editing

PermaLink

Caitlin McDermott-Murphy

The Harvard Gazette

Related: Genetic Engineering & Biotechnology News, Nature Biotechnology, Nature

"Milk and Health" researchers probe the commonly believed health benefit of high milk intake, found thin evidence, while concerns on various adverse health outcomes remain

We reviewed over 100 studies and conclude that milk recommendations for Americans are not based in evidence

PermaLink

Dr. David Ludwig

Elemental-a Medium publication

Related: @NEJM, New England Journal of Medicine (NEJM), @EricTopol

Ongoing clinical trial of Remdesivir, the promising coronavirus drug developed by Gilead, is struggling to recruit patients in China

Patients in the test must not have taken other treatments within 30 days

PermaLink

Staff Writer

Wall Street Journal

Related: Genetic Engineering & Biotechnology News, The Motley Fool, BioSpace, @joel_mossong, ClinicalTrials.gov

Immunologist Jeffrey Bluestone leaves Parker Institute CEO post to start Sonoma BioTx to develop regulatory T cell-based cell therapy to "restore a state of self-tolerance" for autoimmune diseases like RA, IBD, multiple sclerosis

primary article image

PermaLink

Alex Keown

BioSpace

Related: @DrBonnie360, STAT, Endpoints News, Science

Pan-Cancer Analysis of Whole Genomes project, releases 6 papers in Nature, 17 in other journals, pictures comprehensively genetic causes of cancer. A massive cancer genome study, PCAWG has 1300 scientists from 750 institutes to study 38 cancers

primary article image

PermaLink

Jocelyn Kaiser

Science

Related: International Cancer Genome Consortium - ICGC, Nature, The Harvard Gazette, @benjraphael, @IcgcArgo, @NCIgenomics

Biogen defeats Mylan's patent challenge to multiple sclerosis drug Tecfidera, rocketing up shares. Tecfidera had 2019 sales of $4.43 billion

primary article image

PermaLink

ADAM FEUERSTEIN

STAT

Related: Financial Times, @business

Clinical trial of Gilead's remdesivir in coronavirus patients to start tomorrow in China. Initially developed to treat Ebola without success, doctor tried remdesivir in first US coronavirus case, patient improved dramatically within 24 hours

PermaLink

Douglas House

Seeking Alpha

Related: Fortune Magazine, TIME (US magazine), The Verge, ClinicalTrials.gov, New England Journal of Medicine (NEJM)

Gates Foundation commits $100 MM to combat coronavirus outbreak. "To improve detection, isolation and treatment efforts; protect at-risk populations in Africa and South Asia; and accelerate the development of vaccines, drugs and diagnostics"

PermaLink

Tedros Adhanom Ghebreyesus

@DrTedros

Related: Fortune Magazine, Bill & Melinda Gates Foundation

Two pharma giants split. Merck to spin off women’s health, legacy brands & biosimilar and keep oncology, vaccines, hospital & animal health. GSK to spin off consumer unit and focus on immunology, genetics & new technologies

PermaLink

Douglas House

Seeking Alpha

Related: @JaredSHopkins, Wall Street Journal, Financial Times

NEJM paper on transmission of coronavirus by asymptomatic carrier in Germany had flawed information. Germany's Robert Koch Institute & Bavarian health ministry interviewed the initial patient and confirmed she had symptoms

PermaLink

Kai Kupferschmidt

Science

Related: STAT, @AndyBiotech, New England Journal of Medicine (NEJM)

US declared coronavirus a public health emergency, to deny foreign nationals to enter US who have traveled to China within the past two weeks, and pose 14-day quarantine for US citizens who had traveled to Hubei China in the past 14 days

PermaLink

Leslie Josephs

CNBC

Related: @SGottliebFDA

BREAKING: WHO declared the coronavirus outbreak a global public health emergency, meanwhile recommended against trade or travel restriction towards China. First U.S. person-to-person transmission case confirmed

PermaLink

World Health Organization (WHO)

@WHO

Related: MarketWatch, BBC

WHO to reconvene expert panel tomorrow (Jan 30, 2020) to decide if the coronavirus (2019-nCoV) outbreak deemed a global public health emergency

PermaLink

Tedros Adhanom Ghebreyesus

@DrTedros

Related: STAT

The world struggling to control the worsening coronavirus crisis, new cases skyrocketed to 4,515 in China with death toll rose to 106. US risks 'remain low' but rapidly evolving, federal officials hope to start vaccine clinical trial in 3 months

PermaLink

Staff Writer

New York Times

Related: NBC, CNBC

CEPI launches 3 accelerated vaccine development programs for novel coronavirus, nCoV-2019: DNA vaccine (US firm Inovio), molecular clamp vaccine (University of Queensland), mRNA vaccine (US firm Moderna & NIAID). Human trial expected April to June

PermaLink

Staff Writer

CEPI-Coalition for Epidemic PreparednessInnovation

Related: University of Queensland, Moderna Therapeutics, Inovio Pharmaceuticals, Inc., @CEPIvaccines

Moderna working with NIH, NIAID, & VRC to develop a vaccine for the deadly coronavirus using its mRNA vaccine technology, along with other companies or organizations. Moderna has produced a cancer vaccine in 40 days using the same technology

PermaLink

Terri Cullen

CNBC

Related: @AIBNatUQ, @krebs_matt, @BeckyQuick

Deadly coronavirus sicken 440, killed nine in China. First US case identified in Washington state. CDC expects more US cases, expanded airports in Chicago and Atlanta to screen airline passengers from Wuhan China for virus symptoms

The coronavirus has sickened hundreds, killed six in China

PermaLink

Betsy McKay

Wall Street Journal

Related: @LouDobbs, @steveusdin1, @business, @CNBC, @AP, @DrNancyM_CDC, @CDCDirector, STAT, CDC

BeiGene's phase 3 pivotal clinical trial of anti-PD-1 antibody tislelizumab for first-line squamous non-small cell lung cancer met primary endpoint. It has already been approved for classical Hodgkin’s lymphoma in China

PermaLink

Staff Writer

BeiGene

Related: @ZolmaxNews, @ESchattner, @drgandara, Seeking Alpha, BioPharma Dive, Endpoints News

WHO calls for emergency meeting to determine if to declare global health emergency for SARS-like virus outbreak. China confirms human-to-human transmission, and 14 healthcare infected with the virus

PermaLink

Helen Branswell

STAT

Related: @DonnaYoungDC, @CBSNews, @rosemaryCNN, @WHO, @DrTedros, @HernandezJavier, @NewsHour, Yahoo, @HelenBranswell, MRC Centre for Global Infectious Disease Analysis, @MRC_Outbreak

Latest News

Reporting, epidemic growth, and reproduction numbers for the 2019-nCoV epidemic: understanding control

21 Feb 2020, 7:31 PM, Ashleigh Tuite, Dalla Lana School of Public Health


Once widely criticized, the Wuhan quarantine bought the world time to prepare for Covid-19

21 Feb 2020, 6:47 PM, Sharon Begley, STAT


Gilead’s Coronavirus Drug Trial Slowed by Lack of Eligible Recruits

19 Feb 2020, 5:40 PM, Staff Writer, Wall Street Journal


MERS Coronavirus Disease Blocked by Remdesivir in Monkeys

18 Feb 2020, 6:06 PM, Staff Writer, Genetic Engineering & Biotechnology News


Report: Gilead Struggling to Find Subjects for COVID-19 Drug Trial

18 Feb 2020, 5:55 PM, Eric Volkman, The Motley Fool


Gilead Struggles to Recruit Patients for Coronavirus Drug Trial in China

18 Feb 2020, 5:48 PM, Mark Terry, BioSpace


More than 80 clinical trials launch to test coronavirus treatments

15 Feb 2020, 6:52 PM, Amy Maxmen, Nature


Base Editing Promise in Treating a Mouse Model of Progeria

14 Feb 2020, 4:52 PM, Kevin Davies, Genetic Engineering & Biotechnology News


A crisper CRISPR

14 Feb 2020, 4:33 PM, Caitlin McDermott-Murphy, The Harvard Gazette


Milk and Health

13 Feb 2020, 3:52 PM, Walter Willett, New England Journal of Medicine (NEJM)


Time to Question Everything You Know About Milk

12 Feb 2020, 3:49 PM, Dr. David Ludwig, Elemental-a Medium publication


Evaluation and minimization of Cas9-independent off-target DNA editing by cytosine base editors

10 Feb 2020, 4:48 PM, Jordan Doman, Nature Biotechnology


Super-precise CRISPR tool enhanced by enzyme engineering

10 Feb 2020, 4:42 PM, Heidi Ledford, Nature


Severe 2019-nCoV Remdesivir RCT

06 Feb 2020, 5:51 PM, Staff Writer, ClinicalTrials.gov


Jeffrey Bluestone steps down as Parker Institute president to develop cell therapies for autoimmune diseases

06 Feb 2020, 4:42 PM, Matthew Herper, STAT


Jeffrey Bluestone exits Parker and switches focus back to autoimmune diseases in cell therapy 2.0 launch

06 Feb 2020, 4:38 PM, John Carroll, Endpoints News


Parker Institute CEO Jeffrey Bluestone Steps Down to Launch Sonoma Biotherapeutics

06 Feb 2020, 4:35 PM, Alex Keown, BioSpace


PCAWG - PANCANCER ANALYSIS OF WHOLE GENOMES

06 Feb 2020, 3:07 AM, Staff Writer, International Cancer Genome Consortium - ICGC


The era of massive cancer sequencing projects has reached a turning point

06 Feb 2020, 2:54 AM, Staff Writer, Nature


Massive cancer genome study reveals how DNA errors drive tumor growth

06 Feb 2020, 2:52 AM, Jocelyn Kaiser, Science